A rollover accident caused a full closure of the westbound lanes earlier this morning.

Photo via ODOT.
Update at 10:07 a.m.:
The accident has been cleared. Fox19NOW reports that one person sustained fatal injuries in the crash.
(Colerain, Oh.) - Traffic remains restricted following an early morning crash on Interstate 275.
The Ohio Department of Transportation reported around 6:27 a.m. that the westbound lanes of I-275 were closed near Ronald Reagan Highway. According to multiple reports, two people were injured there in a rollover accident.
One lane has reopened, but two lanes remain closed
Motorists should expect further delays.

UPDATE: All Westbound Lanes Reopen on Carroll Cropper Bridge
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